Dominic D’Agostino is an Assistant Professor in the Department of Molecular Pharmacology and Physiology at the University of South Florida and teaches courses in neuropharmacology, medical biochemistry and metabolism. His research is focused on hyperbaric medicine, nutritional strategies and ketone supplementation for the metabolic management of neurological diseases, cancer and muscle wasting diseases. Metabolic therapies can be used to treat a wide variety of disorders linked pathophysiologically to metabolic dysregulation.
Cancer is characterized by metabolic dysregulation and is responsive to therapies that lower blood glucose, reduce insulin and elevate blood ketones. D’Agostino’s laboratory uses in vivo and in vitro techniques to understand the physiological, cellular and molecular mechanism of specific therapies, including radio-telemetry (EEG, EMG), electrophysiology, fluorescence microscopy, hyperbaric laser confocal microscopy, hyperbaric atomic force microscopy (AFM), biochemical assays, in vivo bioluminescence tumor, behavioral tests and exercise performance testing. He pursues his work on behalf of a number of government organizations, including Office of Naval Research, Department of Defense and private organizations. Naval Research, Department of Defense and private organizations.